Data Manipulation / Data import for Medical Orders

I have a excel spreadsheet with about 13,000 different medical orders that needs some data manipulation and addition. It does not need to stay in an excel spreadsheet. If using a database such as MySQL or SQLserver or even Access makes it easier, I am game. This will eventually be used in a program that uses JAVA, Silverlight, or Flash. There are 2,500 unique orders meaning that there are about 7-9 different ways of ordering the same thing such as: MRI, brain, with contrast Magnetic resonance imaging of brain with contrast brain MRI with contrast head MRI with contrast etc. See word document for more details.